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Title: DNA: The Secret of Life by James D. Watson, Andrew Berry ISBN: 0-375-41546-7 Publisher: Knopf Pub. Date: 01 April, 2003 Format: Hardcover Volumes: 1 List Price(USD): $39.95 |
Average Customer Rating: 4.83 (12 reviews)
Rating: 5
Summary: Outstanding Science Writing
Comment: When I picked up James D. Watson's "DNA: THE SECRET OF LIFE" it
didn't seem an entirely promising read. It looked like it might be
just another uninspired "rehash" survey of the subject of genetics
(and genomics and so on), an impression reinforced by Watson's
comments in the foreword that it was partly derived from a TV series
commemorating the 50th anniversary of the discovery of the DNA double
helix by Watson and his colleague, Francis Crick, which won the two
the Nobel Prize.
On reading into "DNA", I quickly realized that this was no mere
rehash, but a very cleanly written and highly readable survey of
genetics. Watson, who has the advantage of a central viewpoint
in the field, neatly weaves together a history of the field, a
technical explanation of it, an exploration of its business and
politics, and something like a professional autobiography.
The writing is outstandingly clear and even witty -- Watson comments
in an understated but clearly pleased fashion how another genetics
researcher named his Siamese cats "Watson" and "Crick". An educated
layperson, clearly the target audience for this book, could hardly
hope for a better introduction to the field, and a nonprofessional
would hardly need to know much more than it provides.
However, this is not saying this is an effortless read. Although by
no means resembling a textbook, "DNA" covers an enormous amount of
ground and range of concepts, and anybody who would claim that he
could pick it up in one reading from end to end is either a real
genius or, more likely, a fraud. My initial reading went cover to
cover and amounted to no more than a survey, to be followed up later
by an extensive session in note-taking.
* Having said all these things, there is a subtler aspect to this
book. In the initial chapters of "DNA", Watson mixed his history of
the early days of modern genetics with a discussion of the "eugenics"
movement, an effort to improve the human race by breeding up
desireables and (more to the point) breeding out undesireables.
Eugenics was weak science and strong racism.
That story was interesting, but I wondered if Watson had a
politically-correct agenda. Further reading showed this not to be the
case -- Watson sees the left-outfield politically correct crowd and
the right-outfield fundamentalist crowd as both obnoxious influences
in his field, and in fact he hardly sees them as being much different.
What emerges is that Watson has an "advocacy agenda". This is not to
say this is the sole focus of this work, it's just that genetics has
certain social and ethical implications that are so unavoidable that
they end up having to be discussed as part of a real survey of the
topic. Fetal genetic screening, for example, has immediate
implications relative to abortion rights, and of course human genetic
engineering is controversial on the face of it.
Watson has his views on such matters, laying out skeins of a general
argument about the social and ethical aspects of his work and then
tying them up in the relatively short final chapter. Of course, there
are weaknesses in his arguments -- for example, he blasts the
authorities for making decisions on a political and not a scientific
basis, which seems a bit silly. (A government organization makes
decisions on a political basis?! REALLY?! Gosh! Who knew?!). His
final argument also was the sort of thing that I wouldn't touch
myself, since long experience with Internet forums told me I would get
nothing out of it but a loud, mad, pointless barking contest.
I do not mock him, however. This is not really my battle but it is
clearly his, and if he seems to struggle with it, well, that's because
it's troublesome stuff. And I on the same wavelength with him in one
respect. He does not see the issues in terms of liberal and
conservative. He sees a clash of two beliefs.
The first belief is that anything that poses any potential public
hazard should be forbidden. The alternative is that people should be
free to do anything that does *not* pose a demonstrable public hazard.
The first belief is that of the control freaks of both left and right.
Watson believes the second and I am in the same camp.
He also does his advocacy the right way, stating his views carefully
and embedding them inside a powerful narrative of facts and details,
which lends them far more credibility than hollow assertions of
opinion. In fact, although Watson's views might infuriate extremists,
the book remains outstandingly informative even if his views are
disregarded. The willingness of the author to confront controversy
does not affect the fact that "DNA" is an excellent piece of science
writing.
* I did catch the author in an exceedly minor error that I point out
not to nitpick but because it's an amusing detail. In his list of
inherited dog traits, he refers to greyhounds as "twitchy".
I used to believe this myself, but there's an "adopt a race dog"
program in my locality, quite a few people around here have
greyhounds as pets -- and all report that the dogs are absolute
couch potatoes who take life easy when not actually chasing
something. On consideration, this is the ideal behavior pattern
for an animal that spends much of its life in a kennel, and an
impressive example of the power of controlled breeding. I think
they just *look* high-strung.
And I suppose while I'm at it, I might add another interesting
inherited dog behavior pattern that wasn't mentioned in "DNA" -- how a
Rottweiler will come up alongside you and give you a small but
powerful sideways NUDGE that will literally throw you for a loop if
you're not expecting it. I was surprised by this when I first ran
into it, but it turns out to be an instinctive herding behavior.
Rating: 4
Summary: Unfolding story of DNA and genetics, and its implications
Comment: James Watson's book, DNA: The Secret of Life, describes the history of DNA and genetics from a scientist who was an eyewitness to the revolutions in genetics. Watson helped discover the 3D structure of the double helix, and led out as a director of the Human Genome Project. There are three main aspects to this book: 1) the recent and on-going history of scientific discoveries in the exploration of genetics, 2) the mechanics of how things work (such as how DNA replicates or is cloned, or how genes are linked to diseases, etc.) and 3) the author's perspective of how life evolved.
Prior to the discovery of DNA, people have been playing around with heredity and the role of inheriting traits in breading animals and agriculture since the beginning of history. But with the developments of science, the study of genetics has brought more light to the subject. Watson talks about the people who contributed to the emerging field of genetics, from Gregor Mendel and Charles Darwin, through the "eugenics" movement of the early 1900's, to the Human Genome Project. By telling the stories of the struggles in science, with the author's frankness, honesty and wit, Watson gains authority and authenticity in the presentation of his information. This book is illuminating and will arouse an interest in the subject of genetics in every reader.
My only personal problem with the book is that the author presents his opinions and perspectives within the text as if his opinions themselves were facts, while in truth there are many issues that are still debated. Watson starts with the founding assumption, or presupposition that life is the result of chance. He makes some unfounded assertions or conclusions that might have other alternate viewpoints. For example, he goes from talking about the chemical properties and processes of DNA replication, jumping to how life began in an "RNA world." He also implies that Arthur Kornberg had created "life in a test tube," while Kornberg himself has written that he did not, in fact, create life. (Journal of Bacteriology)
Watson also asserts that, "The Human Genome Project has proved Darwin more right than Darwin himself would ever have dared dream." But on what basis can he say this? The HGP merely sequenced and mapped DNA and cannot prove anything by itself. Watson employs circular thinking to support evolutionary claims: "proofs" that are founded on the presupposition that humans are results of evolution. The primary argument for evolution is the similarity between all biological systems. But, what if all biological systems were designed similarly on purpose? If something works well in one place, why redesign it? Watson believes that the "grandest mission" of molecular biology is to answer questions about ourselves and our origins as a species. But, as long as scientists start with the presupposition that humans are the result of evolution, the results will always be interpreted that way. So my only caution is that you should distinguish what is actually fact and what is merely the author's speculation.
Anyway, I recommend this book to anyone who is interested in the subject of genetics. Watson presents almost every aspect of the subject in clear detail, and he is frank about the ethical and social implications of the discoveries that are sure to challenge traditional ways of thinking.
Rating: 5
Summary: DNA is a wonderful thing in modern society
Comment: ABSTRACT
DNA - The Secrets of Life
Authors - James D. Watson with Andrew Berry
Random House, Inc., New York
This book DNA - The secrets of Life goes into depth on more then several subjects on many different levels. The book starts by introducing and walking you through the History or beginning of genetics from Mendel to Hitler. The book is able to answer most all questions/concerns and clarifies any confusion that may be had.
Several chapters in the book or sections, if you will, discuss DNA itself. They start by introducing it as the Double Helix in chapter 2. They go on to further explain throughout the book the coding of DNA and the molecules that are customized in the DNA double helix strand. DNA - The Secrets of Life also writes about the roll DNA plays in Biotechnology and human past and evolution.
The book takes a slight turn at chapter 10 when the topic of DNA comes up in court cases and how it is so useful and highly effective in today's law firms. In the following chapters of the book it presents the idea of Genetic Diseases and how to hunt down the "odd gene out" that is mutated and causes the initial problem. The book continues on by writing of how genetic diseases may be prevented or treated. This chapter presents insight into the cure and the factors and results that play into finding a cure into genetic diseases.
The book ends with a bang of a chapter that asks the question: Who are we? Nature vs. Nurture.
Marc Brien wrote this Abstract
This book brought me to my feet and made me applaud and cheer outloud. It was a delightful book that shared the history/current and possible future discoveres with DNA
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Title: The Double Helix : A Personal Account of the Discovery of the Structure of DNA by James D. Watson ISBN: 074321630X Publisher: Touchstone Books Pub. Date: 12 June, 2001 List Price(USD): $14.00 |
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Title: Isaac Newton by James Gleick ISBN: 0375422331 Publisher: Pantheon Books Pub. Date: 13 May, 2003 List Price(USD): $22.95 |
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Title: Nature Via Nurture : Genes, Experience, and What Makes Us Human by Matt Ridley ISBN: 0060006781 Publisher: HarperCollins Pub. Date: 29 April, 2003 List Price(USD): $25.95 |
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Title: Watson and DNA: Making a Scientific Revolution by Victor K. McElheny ISBN: 0738203416 Publisher: Perseus Publishing Pub. Date: 07 January, 2003 List Price(USD): $27.50 |
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Title: Genes, Girls, and Gamow: After the Double Helix by James D. Watson ISBN: 0375412832 Publisher: Knopf Pub. Date: 29 January, 2002 List Price(USD): $26.00 |
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