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Title: The Pathological Protein: Mad Cow, Chronic Wasting, and Other Deadly Prion Diseases by Philip Yam ISBN: 0-387-95508-9 Publisher: Copernicus Books Pub. Date: June, 2003 Format: Hardcover Volumes: 1 List Price(USD): $27.50 |
Average Customer Rating: 4.8 (5 reviews)
Rating: 5
Summary: Easily the best book of its kind
Comment: Philip Yam's book The Pathological Protein is easily the best book of its kind. Written in clear, simple language for the non-specialist audience, The Pathological Protein is a thoroughly comprehensive, concise and, above all, scientifically accurate review of BSE and related diseases. Yam has been writing and editing for Scientific American since 1989 and this, his first book, demonstrates the high standard to which all science writers ought to aspire.
The first chapter of The Pathological Protein describes, from a very human perspective, the effects of variant Creutzfedt-Jakob disease on one victim, 19 year-old Stephen Churchill, and his family. From this tragedy, Yam then goes on to review the history of CJD and the mysterious diease 'kuru', which reached epidemic proportions amongst the Fore people of Papua-New Guinea because of their cannibalistic funerary rites. After discussing the hereditary transmissible spongiform encephalopathies (TSEs) of humans, outlines what is known of the TSEs of animals. Philip Yam's reviews of scrapie, BSE, transmissible mink encephalopathy and chronic wasting disease are up-to-date, interesting, and extremely readable.
There is an interesting episode related in the book. Carlton Gajdusek had been searching, unsuccesfully, for the cause of kuru. William Hadlow, and American scrapie researcher on a secondment to the United Kingdom, visited the Wellcome Medical Museum in London to look at a display on kuru that Gajdusek had prepared. It was Hadlow who first noticed the very close resemblance between kuru and scrapie. The similarities in epidemiologic features, general clinical pattern and the neurohistologic changes led him to the realisation that these diseases were probably mmebers of the same family. As a result of Hadlow's insight transmission experiments were started which, eventually, led to our current understanding of the TSEs
This book covers the hypotheses for the origins of BSE, the evidence for the link between BSE and vCJD, current methods and problems of diagnosis of the TSEs, and the search for cures. Philip Yam clearly is thoroughly versed in the scientific literature of the TSEs, but also interviewed a broad range of scientists, consumers advocates and regulators. So, he knows what he is writing about, and this is made evident by the clarity and accuracy of his explanations. Although there is no 'dumbing down' of a difficult and complex subject, the author has written a book which makes his subject easily accessible to the non-specialist reader. The book is referenced, well indexed, has a useful glossary and also suggests sources for further information, including the more useful web sites and organisations providing suport and help for families of CJD victims. While the book is written for the interested lay person, I would have no hesitation in recommending Philip Yam's The Pathological Protein to veterinarians and colleagues who want an interesting, thorough and current review of these fascinating diseases.
Rating: 5
Summary: A must read for a better understanding of mad cow disease!
Comment: An easy read even for people without a scientific background. The author takes you through a thorough exploration of the threats of mad cow and other related diseases. You may never look at beef the same way again.
Rating: 4
Summary: If you eat beef or wild game, you need to read this.
Comment: This is a concise yet indepth treaty of all spongiform disorders.Yam has left nothing out. To fully appreciate the prion biochemistry a basic understanding of replication and genetics is needed. This is an informative book without losing the reader.I highly recommend it.
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Title: How the Cows Turned Mad by Maxime Schwartz, Edward Schneider ISBN: 0520235312 Publisher: University of California Press Pub. Date: 01 February, 2003 List Price(USD): $24.95 |
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Title: DEADLY FEASTS: Tracking The Secrets Of A Terrifying New Plague by Richard Rhodes ISBN: 0684844257 Publisher: Simon & Schuster Pub. Date: 01 May, 1998 List Price(USD): $13.00 |
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Title: The New Killer Diseases: How the Alarming Evolution of Mutant Germs Threatens Us All by Elinor Levy, Mark Fischetti ISBN: 0609609947 Publisher: Crown Publishers Pub. Date: 15 July, 2003 List Price(USD): $24.95 |
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Title: Fatal Protein: The Story of Cjd, Bse, and Other Prion Diseases by Rosalind Ridley, Harry Baker, Harry F. Baker ISBN: 0198524358 Publisher: Oxford University Press Pub. Date: 01 June, 1998 List Price(USD): $54.50 |
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Title: The Trembling Mountain: A Personal Account of Kuru, Cannibals, and Mad Cow Disease by Robert Klitzman ISBN: 0738206148 Publisher: Perseus Publishing Pub. Date: 07 August, 2001 List Price(USD): $24.00 |
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