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Title: Color Atlas of Nerve Biopsy Pathology by Shin J. Oh ISBN: 0-8493-1676-6 Publisher: CRC Press Pub. Date: 29 August, 2001 Format: Hardcover Volumes: 1 List Price(USD): $179.95

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Average Customer Rating: 1 (1 review)

Rating: 1
Summary: nerve pathology
Comment: This book is an attempt to provide an overview of peripheral neve pathology using color light microscopy photomicrographs of frozen, paraffin, and, to a very limited degree, semithin and teased nerve fiber preparations. I will not attempt to comment on the anecdotal clinical cases nor on the electrodiagnostic data provided. From a pathology standpoint, this book by Dr. Oh (not editor) falls far short of its goal. Ignoring the troubling misspellings, inadequately referenced and often controversial statements, figure and legend miscorrelations, and illustrations of tissues other than nerve there are numerous errors in the pathology. Space precludes a thorough review. A most troubling recommendation is that the freshly biopsied nerve is allowed to autolyze for 15 minutes, apparently at room temperature, "for reducing contraction artifact". Lacking contractile elements, nerves do not contract. They are very susceptable to autolysis, crush artifact, and fixation artifact such as shrinkage from hypertonic fixative. The illustrations contain, apparently nwittingly, many of these artifacts partly resulting from the recommended techniques. The preferred preparation for analysis, frozen sections, are cut at 10 microns. Since most of the fine endoneurial structures of interest are considerably smaller than 10 microns, much of the finer details are difficult to analyze at this thickness. This is one reason why 1 micron plastic sections are the standard preparations, supplimented with well fixed 3 micron paraffin sections to facilitate study of elements less obvious in plastic. There are many errors in histological identification and a number of photographs are out of focus. The index is very incomplete. I found it very unpleasant to review this book, and cannot recommend it.